Influence of non-penetrating glaucoma surgery on aqueous outflow facility in isolated porcine eyes
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چکیده
منابع مشابه
Influence of intraocular pressure on aqueous outflow facility in enucleated eyes of different mammals.
Freshly enucleated monkey, calf, and human eyes were quantitatively perfused with mock aqueous humor through the anterior chamber by a constant pressure technique. After baseline perfusion at 15 mm Hg, intraocular pressure was raised to 45 mm Hg and later reduced back to 15 mm Hg. Calf and human (both adult and infant) eyes had lower outflow facilities at 45 than at 15 mm Hg. However, four type...
متن کاملBlebbistatin, a novel inhibitor of myosin II ATPase activity, increases aqueous humor outflow facility in perfused enucleated porcine eyes.
PURPOSE To investigate the specific role of myosin II, a critical biochemical determinant of cellular contraction, in modulation of aqueous humor outflow facility through the trabecular meshwork (TM) pathway. METHODS Expression of the nonmuscle myosin II heavy chains (IIA, IIB, and IIC) in human TM and ciliary body (CB) cells was determined by RT-PCR analyses. The effects of inhibition of myo...
متن کاملNon-Penetrating Glaucoma Filtering Surgery-An overview
Trabeculectomy remains the standard surgery for intraocular pressure control for glaucoma. It involves a full thickness penetration of sclera, to allow aqueous seepage to subconjunctival space under a scleral flap. However, it carries the risk of serious bleb related complications like overfiltration, hypotony and consequent persistent choroidal detachment, shallow anterior chamber, cataract, p...
متن کاملObservations on the facility of aqueous outflow in closed-angle glaucoma.
IN closed-angle glaucoma the darkroom test may be followed by a rise in ocular tension and a measurable fall in the facility of aqueous outflow. In an earlier communication (Foulds, 1956), it was suggested that this decrease in the facility of outflow was a more reliable guide to the occurrence of angle closure during the test, than the rise in ocular tension, particularly in early cases of clo...
متن کاملHow does nonpenetrating glaucoma surgery work? Aqueous outflow resistance and glaucoma surgery.
Histologic, experimental, and theoretical studies of the aqueous outflow pathways point toward the juxtacanalicular region and inner wall of Schlemm's canal as the likely site of aqueous outflow resistance in the normal eye. At least 50% of the aqueous outflow resistance in the normal eye and the bulk of the pathologically increased resistance in the glaucomatous eye resides in the trabecular m...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 2004
ISSN: 0007-1161
DOI: 10.1136/bjo.2003.035535